About Us

RxParadigm is led by Mesfin Tegenu, MS, RPh, a visionary entrepreneur and nationally recognized leader in the Pharmacy Benefit Management (PBM) industry. With a proven track record of innovation and market disruption, Mesfin previously founded and scaled one of the nation’s largest PBMs serving primarily government-funded programs—growing it into a $3 billion enterprise that delivered pharmacy benefits to millions across multiple states. His achievements were built upon cutting-edge prescription claims processing technology and unrivaled formulary and rebate strategies that reshaped industry best practices.

Driven by a relentless commitment to transforming the U.S. drug supply chain, Mesfin founded his second company to tackle systemic inefficiencies that drain value from payers, providers, and patients alike. It was during this mission that he identified a glaring void in rebate management infrastructure—a gap that led to the creation of RxParadigm, a next-generation platform engineered to bring precision, speed, and transparency to rebate administration.

Following the successful launch of its end-to-end rebate administration system, RxParadigm set its sights on one of the most complex challenges in healthcare: the 340B program. Leveraging its technology and expertise, the company is now delivering transformative solutions that empower Covered Entities, streamline manufacturer operations, and restore balance to the pharmaceutical ecosystem.

With Mesfin’s leadership, RxParadigm is not merely solving today’s inefficiencies—it is redefining how value flows through the drug supply chain, setting a new standard for accountability, innovation, and equitable access in the healthcare marketplace.